| EFFECT OF DIFFERENT INTRA-CANAL MEDICAMENTS ON BIOFILM GROWTH IN ROOT CANALS: AN IN VITRO STUDY |
| Paper ID : 1065-YRC2022 (R1) |
| Authors |
|
Hesham Moheb Mansour * Suez canal university |
| Abstract |
| Enterococcus faecalis (E. faecalis) is a gram positive, facultative anaerobic bacterium which plays a major role in endodontic secondary infection. E. faecalis also can live in severe conditions, as high pH and temperatures or lack of nutrients and has defense against surfactants (1). Biofilm is a mode of microbial growth where dynamic communities of interacting sessile cells are embedded in a self-made matrix of extracellular polymeric substances and irreversibly attached to each other as well as a solid substratum (4).Calcium hydroxide based paste (Ca(OH)2) is considered one of the oldest and widely used intra-canal medication. It was originally introduced to the field of endodontics by Herman in 1920 as a pulp-capping agent. It promotes destruction of bacterial cytoplasmic membrane, and microbial DNA due to its high pH. Moreover, it induces hard tissue like structure formation by stimulating alkaline phosphatase enzyme (6).. Metronidazole is one of the mainstay drugs for the treatment of anaerobic bacterial infections,Recently chitosan plays an important role in many dental fields and has an excessive consideration in dental research |
| Keywords |
| Enterococcus faecalis; biofilm; chlorhexidine; metronidazole; Calcium hydroxide |
| Status: Accepted (Poster Presentation) |
