| APPLICABILITY OF NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO IN EARLY DIFFERENTIATION BETWEEN ENDOMETRIAL HYPERPLASIA AND ENDOMETRIAL CANCER IN CASES WITH ABNORMAL UTERINE BLEEDING |
| Paper ID : 1066-YRC2022 |
| Authors |
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Mo'men Mohamed Attia *1, Mohamed Amro Mohamed Samy Khodair2, Khaled Ahmed Atwa2 1Suez canal unversity 2Suez Canal University |
| Abstract |
| Abstract: Objective: To investigate the applicability of neutrophil lymphocyte ratio (NLR) and the platelet lymphocyte ratio (PLR) in early differentiation between endometrial hyperplasia and endometrial cancer in cases with abnormal uterine bleeding. Patients and Methods: A descriptive study was carried out in the Department of Obstetrics and Gynecology at Suez Canal University Hospital and Suez General Hospital, 159 pre and postmenopausal women with abnormal uterine bleeding were divided according to the result of endometrial biopsy into 3 groups; 73 normal endometrium, 68 endometrial hyperplasia (EH) and 18 endometrial cancer (EC). Transvaginal pelvic ultrasonography and laboratory tests included complete blood count, random blood sugar, coagulation profile, liver and kidney function tests were performed just before dilatation and curettage procedure. NLR &PLR were calculated. Results: There was significant increase in the total leucocytic count and neutrophil in EC and atypical EH groups in comparison to control group and EH without atypia group (P <0.0001). NLR was 2.24± 1.37, 2.31± 0.61, 3.08± 1.45 and 3.96± 1.70 in the control, EH without atypia, EH with atypia and EC groups respectively, NLR and PLR increased among the EC and atypical EH groups in comparison to control group and EH without atypia group, the difference was statistically highly significant (P <0.0001and P= 0.001 respectively). There was significant correlation between EC Staging and grading versus TLC, Neutrophil, NLR and PLR (p < 0.05). Conclusion: NLR and PLR are simple and reliable tests that can be used in early differentiation between endometrium hyperplasia and endometrium cancer. |
| Keywords |
| Endometrial cancer, hyperplasia, NLR, PLR. |
| Status: Accepted (Poster Presentation) |
